For a complete list, view Dr. Maron's
PubMed
Maron JL, Jones GB. How sensors, devices, and biomarkers can transform precision medicine: perspectives from a clinical and translational science institute. Clin Ther 2018;40:345-348.
Khanna P, Maron JL, Walt DR. Development of a rapid salivary proteomic platform for oral feeding readiness in the preterm newborn. Front Pediatr 2017;5:268.
Maron JL. Forgotten No More: How policy guideline changes are bringing newborns, infants, and children to the forefront of drug discovery and testing. Clin Ther 2017;39:1918-1919.
Barlow SM, Maron JL, Alterovitz G, Song D, Wilson BJ, Jegatheesan P, Govindaswami B, Lee J, Rosner AO. Somatosensory modulation of salivary gene expression and oral feeding in preterm infants: Randomized controlled trial. JMIR Res Protoc 2017;6:e113. doi: 10.2196/resprot.7712.
Hassaneen M, Maron JL. Salivary diagnostics in pediatrics: Applicability, translatability, and limitations. Front Public Health 2017;5:83.
Khanna P, Johnson KL, Maron JL. Optimal reference genes for RT-qPCR normalization in the newborn. Biotech Histochem 2017;92:459-466.
Bringing salivary diagnostics into the 21st century. Maron JL. Clin Ther. 2015 Mar 1;37(3):496-7. doi: 10.1016/j.clinthera.2015.02.007. Epub 2015 Mar 5. No abstract available. PMID: 25748292
Computational gene expression modeling identifies salivary biomarker analysis that predict oral feeding readiness in the newborn. Maron JL, Hwang JS, Pathak S, Ruthazer R, Russell RL, Alterovitz G. J Pediatr. 2015 Feb;166(2):282-8.e5. doi: 10.1016/j.jpeds.2014.10.065. PMID: 25620512
Detection and potential utility of C-reactive protein in saliva of neonates.
Iyengar A, Paulus JK, Gerlanc DJ, Maron JL.
Front Pediatr. 2014 Nov 21;2:131. doi: 10.3389/fped.2014.00131. eCollection 2014.
PMID: 25485262
Performing discovery-driven neonatal research by transcriptomic analysis of routinely discarded biofluids.
Maron JL, Dietz JA, Parkin C, Johnson KL, Bianchi DW.
J Matern Fetal Neonatal Med. 2012 Dec;25(12):2507-11. doi: 10.3109/14767058.2012.717126. Epub 2012 Aug 27.
PMID: 22920923
Insights into Neonatal Oral Feeding through the Salivary Transcriptome.
Maron JL.
Int J Pediatr. 2012;2012:195153. doi: 10.1155/2012/195153. Epub 2012 Jul 10.
PMID: 22844301 [PubMed] Free PMC Article
Neuropeptide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate.
Maron JL, Johnson KL, Dietz JA, Chen ML, Bianchi DW.
PLoS One. 2012;7(5):e37870. doi: 10.1371/journal.pone.0037870. Epub 2012 May 21.
PMID: 22629465
Selected Presentations
“Sex Matters: Uncovering the Molecular Mechanisms for Disparities in Neonatal Clinical Outcomes through Salivary Gene Expression Analysis.” University of Los Angeles, January, 2019, Los Angeles, CA.
“Tackling and Appreciating Biological Variability in Neonatal Salivary Gene Expression Analysis.” North American Saliva Symposium, Houston, TX, October, 2018.
“Can Salivary Microbial Colonization Predict Disease Outcome in the Newborn North American?” Saliva Symposium, Portland, OR. September, 2017.
“The Promises and Challenges of Integrating Salivary Diagnostics into Newborn Care, First Asia-Pacific Saliva Symposium,” Guangzhou, China February, 2017.
“The (RNA) Sequence of Events: Using Advanced Genetic Platforms to Uncover Disruptive Developmental Pathways Affecting Oral Feeding Success in the Newborn.” Pediatric Academic Society Meeting, May, 2017, San Francisco, CA
“Can Salivary Microbial Colonization Predict Disease Outcome in the Newborn?” North American Saliva Symposium, Portland, OR, September, 2017.
“Advancing Pediatric Salivary Diagnostics – One Drop at a Time.” 3rd Annual North American Saliva Symposium, New York, New York , December, 2016.
“Translating the Transcriptome: Insights into Neonatal Oral Feeding through the Salivary Gene Expression Analysis.”Neonatal Grand Rounds, Washington University, St. Louis, July 2015.
North American Saliva Symposium, Seattle, WA
“Beyond Childhood Caries: The Clinical Implications of Salivary Diagnostics in the Pediatric Population” December, 2015.
“Bringing Salivary Diagnostics to the Neonatal Bedside.” Perinatal Research Society, Itasca IL, September, 2016.
NICHD R01HD097081-01A1
2019-2024
Salivary Diagnostics for Sepsis Screening in the Newborn
The overall goal of this multi-center research grant is to integrate the first comprehensive, ultra-sensitive multiplexed salivary sepsis-screening platform into neonatal care.
Role: Multi-site Principal Investigator
NIH National Center For Advancing Translational Sciences of the (U01TR002271)
08/15/2018 – 07/31/2023
Precision Medicine in the Diagnosis of Genetic Disorders in Neonates.
The overall goal of this multi-center research study is to study the integration of targeted genomic sequencing into neonatal diagnosis and care.
Role: Co-Principal Investigator
NICHD (R01 HD086088-01)
4/1/2016-3/31/2021
Somatosensory Modulation of Salivary Gene Expression and Oral Feeding in Preterm Infants.
The overall goal of this multi-center research proposal is to pair the expertise of Co-PIs Drs. Steven Barlow and Jill Maron to develop an innovative, novel, personalized and integrative approach that directly addresses the important need for oral feeding treatment strategies for the extremely premature infant population.
Role: Co-Principal Investigator
2013-2018,
A Molecular Assessment of the Consequences of Preterm Birth
NICHD R01 HD076140-04
The aim of this study is to further our understanding of the causes of short-term complications and longer-term health outcomes following preterm birth through comprehensive transcriptomic analyses of cord blood.
Role: Co-Investigator
Tufts Clinical and Translational Science Institute Pilot Award
5/1/16-4/30/17
FOXP2 Gene Expression Levels: A Noninvasive Biomarker to Predict both Oral Feeding and Speech-Language Success.
The goal of this grant is to explore the relationship between quantitative levels of FOXP2 in neonatal saliva and oral feeding and speech language outcomes in the premature newborn.
Role: Co-Principal Investigator
Gerber Foundation
2012-2013
NOuRISH Platform: Neonatal Oral-feeding Readiness In High-throughput Salivary Diagnostics
The goal of this grant is to test a novel high-throughput salivary transcriptomic platform for the accurate and objective determination of oral-readiness to feed in the newborn population.
Role: Principal Investigator
K08 NIH/NICHD (K08HD059819)
2009-2014
Neonatal Salivary Genomic Profiles to Assess Feeding Tolerance and Disease.
The goal of this study is to generate, through the use of noninvasive neonatal salivary transcriptomic profiles, important and novel genomic and proteomic data that will allow for comprehensive analysis of neonatal developmental and pathological pathways and protein networks. We aim to identify key biomarkers that may predict neonatal feeding complications, aid in our understanding of such complications, and become gene targets for future therapy.
Role: Principal Investigator
Tufts University Sch. of Med. Earl P. Charlton Fund Research Award
2011-2012
Understanding Developmental Transcriptional Regulation in Premature Neonates Learning to Feed.
The goal of this grant was to better understand transcriptional regulatory processes as they relate to neonatal feeding morbidities.
Role: Principal Investigator
Child Health Research Award
2009-2011
Charles H. Hood Foundation
Neonatal Salivary Genomic Profiles to Assess Feeding Tolerance and Disease.
This goal of this grant was to identify key neurological and neuromuscular regulatory pathways involved in the learning process of oral feeding in premature neonates through salivary gene expression profiles.
Role: Principal Investigator
Pediatric Research Grant
2008-2009
Tufts Medical Center
The goal of this grant was to identify potential biomarkers in the neonatal salivary transcriptome that would provide insight into a newborn’s readiness to feed, feeding intolerance, and gastrointestinal pathology.
Role: Principal Investigator
Natalie V. Zucker Award
2008-2009
Tufts University School of Medicine
Neonatal Salivary Genomic Profiles to Assess Feeding Tolerance and Disease.
The goal of this grant was to test the hypothesis that neonatal salivary gene expression analyses would provide novel information about a newborn’s readiness to feed, feeding intolerance, and gastrointestinal pathology.
Role: Principal Investigator