Lymphomas

Lymphoma is a cancer of the lymphatic system. One type is Hodgkin disease, and the other types are called non-Hodgkin lymphoma.

Programs + Services


Blood and Marrow Transplant Program

The Blood and Marrow Transplant Program at Tufts Children's in Boston provides hematopoietic cell transplants for children with cancer and blood disorders.
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Leukemias and Lymphomas Program

The specialists at the Tufts Children's Hospital have expertise treating childhood leukemia and lymphoma. Learn more and request an appointment.
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Doctors + Care Team

Jason Law, MD

Jason Law, MD

Accepting New Patients

Virtual Appointments Available

Title(s): Chief, Pediatric Hematology Oncology; Site Principal Investigator, Children’s Oncology Group and Neuroblastoma Medulloblastoma Translational Research Consortium Trials; Director, Pediatric Bone Marrow Transplantation; Assistant Professor, Tufts University School of Medicine
Department(s): Pediatrics, Pediatric Hematology/Oncology
Appt. Phone: 617-636-5535
Fax #: 617-636-7738

Pediatric hematology, oncology, bone marrow transplant

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Blythe G.  Thomson, MD

Blythe G. Thomson, MD

Accepting New Patients

Title(s): Pediatric Hematologist/Oncologist
Department(s): Pediatrics, Pediatric Hematology/Oncology
Appt. Phone: 617-636-5535
Fax #: 617-636-7738

Pediatric Hematology/Oncology

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Cathy G. Rosenfield, MD

Cathy G. Rosenfield, MD

Accepting New Patients

Virtual Appointments Available

Title(s): Co-Director, Tufts University School of Medicine Hematology Course; Associate Clinical Professor, Tufts University School of Medicine
Department(s): Pediatrics, Pediatric Hematology/Oncology
Appt. Phone: 617-636-5535
Fax #: 617-636-7738

Hemophilia and other bleeding disorders, prothrombotic disorders, sickle cell and other hemoglobinopathies, general hematology

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Hannah Fassel, MD

Hannah Fassel, MD

Accepting New Patients

Virtual Appointments Available

Title(s): Hematologist/Oncologist; Assistant Professor, Tufts University School of Medicine
Department(s): Pediatrics, Hematology/Oncology
Appt. Phone: 978-937-6362.
Fax #:

Anemia, bleeding disorders, thrombosis, general hematology, and childhood cancers such as leukemia and lymphoma.

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Laura M.  Wiltsie, DO

Laura M. Wiltsie, DO

Accepting New Patients

Virtual Appointments Available

Title(s): Pediatric Hematologist/Oncologist; Assistant Professor, Tufts University School of Medicine
Department(s): Pediatrics, Hematology/Oncology
Appt. Phone: 617-636-5535
Fax #: 617-636-7738

Solid tumors, brain tumors

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Tishi Shah, MD

Tishi Shah, MD

Accepting New Patients

Virtual Appointments Available

Title(s): Attending Physician, Pediatric Hematology Oncology; Professor, Tufts University School of Medicine
Department(s): Pediatrics, Pediatric Hematology/Oncology
Appt. Phone: 617-636-5535
Fax #: 617-636-7738

Pediatric hematology oncology, vascular anomalies

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Research + Clinical Trials


A Phase 3 Trial Investigating Blinatumomab (IND# 117467, NSC# 765986) in Combination with Chemotherapy in Patients with Newly Diagnosed Standard Risk or Down syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients with Localized B-Lymphoblastic Lymphoma (B-LLy)

This phase III trial studies how well blinatumomab works in combination with chemotherapy in treating patients with or without Down syndrome and newly diagnosed, standard risk B-lymphoblastic leukemia or B-lymphoblastic lymphoma. Monoclonal antibodies, such as blinatumomab, may induce changes in body's immune system and may interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as vincristine, dexamethasone, prednisone, prednisolone, pegaspargase, methotrexate, cytarabine, mercaptopurine, doxorubicin, cyclophosphamide, and thioguanine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Leucovorin decreases the toxic effects of methotrexate. Giving monoclonal antibody therapy with chemotherapy may kill more cancer cells. Giving blinatumomab and combination chemotherapy may work better then combination chemotherapy alone in treating patients with B-ALL. This trial also assigns patients into different chemotherapy treatment regimens based on risk (the chance of cancer returning after treatment). Treating patients with chemotherapy based on risk may help doctors decide which patients can best benefit from which chemotherapy treatment regimens.
More information about research and clinical trials